Technical Symposium MD
This Symposium focuses on the practical applications of the synthesis, characterization, and performance (both in vitro and in vivo) of coatings and modified surfaces designed for biomedical applications. The symposium is devoted to creating a friendly hub platform to promote research discussions between material scientists, engineers, coating experts, nanotechnologists, and clinicians. Papers are solicited in areas related to bioactive and biocompatible coatings for implants (e.g., orthopedic, dental, spinal, etc.), cardio-vascular stents, drug delivery, and biosensing. Examples of research topics sought are hydroxyapatite coatings, biomimetic and bio-inspired coatings, antimicrobial, anti-biofouling, drug-eluting coatings, blood-compatible coatings, electrospun coatings, biofunctionalization of materials surfaces such as tissue engineering scaffolds by wet chemical and plasma methods, cell-surface interactions, bio-lubrication and bio-tribology, and processing and characterization of biomaterial surfaces. Studies of the interactions between coatings and the biological environment, including tribocorrosion and other degradation mechanisms, are also welcome. Moreover, research on the effect of biomaterial coatings on biological behavior, such as cell growth, adhesion, and gene expression, is sought. Contributions in retrieval implant analysis, releasing metal ions/particles, smart/intelligent surfaces, and potential clinical concerns will also be considered. A new key interest is the applications of coatings in additive manufacturing, as many novel 3D-printed implants benefit from surface coatings to promote osseointegration and, more generally, biocompatibility.
MD1. Surface Coatings and Surface Modifications in Biological Environments
This session addresses coatings and surface modifications utilized in biomedical applications. These modifications aim to enhance the performance characteristics or provide additional functionalities to implants, medical devices, or surgical instruments. The coatings and surface modifications serve various functions, including improving biocompatibility, promoting cell proliferation and viability, reducing restenosis, preventing thrombus formation, regulating metallic ion release, and resisting corrosion, wear and fatigue tribocorrosion, and wear. These functionalities are evaluated in both laboratory settings (in vitro) and within living organisms (in vivo). In addition, the regulated biological responses to the surfaces can be utilized for diagnostic and monitoring purposes, such as early prediction of diseases such as cancer or neurological disorders, through readily available body fluids, urine, or saliva. This session seeks to explore clinical applications and physiological responses to material systems used for tissue regeneration, implantable sensors, and smart drug delivery, among other things. The scope extends to computational, analytical, and experimental studies investigating coated biomaterials’ underlying mechanisms and diverse behaviors. Your research, with its potential to directly contribute to these practical applications, holds immense value for the advancement of the field. We encourage you to share your findings and insights with our community of researchers and practitioners.
Keywords: Coatings and Surface modifications of biomaterials, Corrosion, Tribology, Tribocorrsion, 3D printing/additive manufacturing, Implants, Retrieval studies, Biosensors and diagnostic devices.
MD1 Invited Speakers:
- Ren-Jei Chung, National Taipei University of Technology, Taiwan
- Chi-Hsien Huang, Ming Chi University of Technology, Taiwan
- Ying-Chih Liao, National Taiwan University, Taiwan
- Ting-Yu Liu, Ming Chi University of Technology, Taiwan, “Noble Nanoparticles Arrays Coating for Electrochemical (EC) and Surface-Enhanced Raman Spectroscopy (SERS) Biosensors”
- Diego Mantovani, University of Laval, Canada
- Mike McNallan, University of Illinois – Chicago, USA
- V. Ram Gopal Rao, Birla Institute of Technology and Science, Pilani, India, “Biosensor Developments”
MD2. Surface Response to Biological Environments, Biointerphases, and Regenerative Biomaterials
The communication interactions between cells/bacteria and biomaterials occur through the surface of the biomaterials. The surface characteristics encompass its topography, chemistry, mechanical properties, surface energy, and redox potentials. These interactions initiate either desirable or undesirable processes. For instance, they can activate signaling pathways that regulate cell adhesion, migration, proliferation, and differentiation into specific desired cell types for various applications. However, they can also facilitate excessive adhesion of microorganisms, leading to the formation of biofilms that pose significant health risks. Gaining a comprehensive understanding of these interaction processes and their relationship with surface properties is crucial knowledge that enables us to create new surfaces or coatings capable of promoting specific biological responses, thereby designing bioactive surfaces. The session welcomes abstracts on the new generation of biomaterials based on regenerative medicine and tissue engineering, potentially competing to replace man’s synthetic materials. Recent developments such as 3D bioprinted bones and tissues, functionally graded materials, nature-mimetic biomaterials, and computational models/AI-driven technology in biomaterials will be strongly recommended for submission.
Keywords: Biocompatibility, Antibacterial properties, Biointerphases, Cell-Material interaction pathways and Mechanisms, Regenerative materials and surfaces, Tissue engineering, 3D Bioprinting, Computational model and AI-driven biomaterials
MD2 Invited Speakers:
- Madhu S. Dhar, University of Tennessee, USA, “Integrating Materials Science with Biology to Advance Tissue Engineering and Regenerative Medicine”
- Samir Iqbal, University of Texas at Rio Grand Valley, USA, “Biomedical Engineering and Diagnostics”
- Huinan Liu, University of California, Riverside, USA
- Murali Sastry, Monash University, Australia, “Bioapplications Using Novel Synthesis Strategies”